The short answer is yes, but how you do it is very, very important. If you make your product the primary focus of your speech, or Q and A, you will bore the audience, or worse, annoy them. Nobody comes to a major conference like TED to hear a product pitch. People come to hear new ideas. You must be able to craft a dynamic, purposeful, wildly creative premise to your speech first, and then strategically weave mentions of your product into the speech as you develop your material.
Take Elon Musk’s brilliant TED Q and A. The premise of his talk is really the nature of innovation, but he manages to use his three current companies, Tesla, SpaceX, and Solar City, as examples. It never really appears that he is promoting his companies, because his first loyalty is to his premise (the nature of innovation). As long as you prioritize your premise and keep it innovative, inclusive, and not sales oriented, then, ironically perhaps, it is safe to do a little selling.